Getting Started
The purpose of this exercise is to acquaint you with some of the factors
involved in the selection of a fungal population resistant to a fungicide.
The exercise will be conducted on a computer simulation model called
Resistan, which simulates selection in a clonal population
(an asexually reproducing, haploid organism). The default parameters in the
model are for a generalized fungus and generic fungicides. For this exercise,
we will want to parameterize Resistan to represent the control of
apple scab
(caused by the fungus, Venturia inaequalis)
with a multi-site fungicide, captan, and a single-site fungicide, benomyl. (To create your
own dataset for a different fungus or for new fungicides, see the
Resistan Model Description.)
To load the parameters,
- Click on
Venturia dataset.
- Highlight
the entire block of text, and
copy
it.
- Start the simulation by clicking on the button in the left margin.
- Click on the Simulation
menu and select Load Data File.
- Click in the window that opens,
paste
your copied text there, and click on the "Load Data File" bar at the
bottom of the window.
You have now parameterized Resistan with the
Venturia data set and are ready to begin the exercises. (Note: to be sure that the
model is properly initialized, you will have to load the Venturia dataset
again before the start of each new exercise. Leave the Venturia dataset window open to facilitate
copying and pasting it repeatedly.)
....proceed to EXERCISE 1
Instructors: See
Instructor Answer Sheet.
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